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Author: Leonard, Stephanie
Resulting in 6 citations.
1. Leonard, Stephanie
Understanding the Relationship of Pregnancy Weight and Weight Change with Infant and Child Health
Ph.D. Dissertation, Department of Epidemiology, University of California, Berkeley, 2017
Cohort(s): Children of the NLSY79, NLSY79, NLSY79 Young Adult
Publisher: ProQuest Dissertations & Theses (PQDT)
Keyword(s): Alcohol Use; Body Mass Index (BMI); Childhood; Childhood Adversity/Trauma; Gestation/Gestational weight gain; Health, Mental/Psychological; Health/Health Status/SF-12 Scale; Household Influences; Parenting Skills/Styles; Parents, Behavior; Pre/post Natal Behavior; Weight

Permission to reprint the abstract has not been received from the publisher.

The second paper identifies longitudinal trajectories of maternal weight from prepregnancy through the postpartum period and assesses the relationship between maternal weight trajectories and offspring obesity in childhood. The third paper determines if maternal history of physical abuse in childhood is related to the risk of offspring overweight in childhood, and whether prepregnancy BMI and gestational weight gain play mediating roles in such an association. These dissertation papers together provide valuable information to help determine ranges of weight gain during pregnancy that minimize risk of adverse infant and child health outcomes. They also intend to stimulate further research to establish a scientific evidence base for creating effective interventions and clinical gestational weight gain guidelines. Promoting healthy weight and weight gain in pregnancy presents a potentially feasible and effective opportunity to improve infant and child health.
Bibliography Citation
Leonard, Stephanie. Understanding the Relationship of Pregnancy Weight and Weight Change with Infant and Child Health. Ph.D. Dissertation, Department of Epidemiology, University of California, Berkeley, 2017.
2. Leonard, Stephanie
Petito, Lucia C.
Rehkopf, David
Ritchie, Lorrene
Abrams, Barbara
Maternal History of Child Abuse and Obesity Risk in Offspring: Mediation by Weight in Pregnancy
Childhood Obesity 13,4 (August 2017): 259-266.
Also: https://www.ncbi.nlm.nih.gov/pubmed/28440693
Cohort(s): Children of the NLSY79, NLSY79
Publisher: Mary Ann Liebert, Inc.
Keyword(s): Alcohol Use; Body Mass Index (BMI); Childhood Adversity/Trauma; Gestation/Gestational weight gain; Health, Mental/Psychological; Household Influences; Obesity; Parental Influences; Weight

Permission to reprint the abstract has not been received from the publisher.

Among every 100 mothers who reported physical abuse in childhood, there were 3.7 (95% confidence interval: -0.1 to 7.5) excess cases of obesity in 2- to 5-year olds compared with mothers who did not report physical abuse. Differences in prepregnancy BMI, but not gestational weight gain, accounted for 25.7% of these excess cases. There was no evidence of a similar relationship for household alcoholism or mental illness or for obesity in older children.
Bibliography Citation
Leonard, Stephanie, Lucia C. Petito, David Rehkopf, Lorrene Ritchie and Barbara Abrams. "Maternal History of Child Abuse and Obesity Risk in Offspring: Mediation by Weight in Pregnancy." Childhood Obesity 13,4 (August 2017): 259-266.
3. Leonard, Stephanie
Petito, Lucia C.
Rehkopf, David
Ritchie, Lorrene
Abrams, Barbara
Weight Gain in Pregnancy and Child Weight Status from Birth to Adulthood in the United States
Pediatric Obesity 12,S1 (August 2017): 18-25.
Also: https://onlinelibrary.wiley.com/doi/10.1111/ijpo.12163
Cohort(s): Children of the NLSY79, NLSY79, NLSY79 Young Adult
Publisher: Wiley Online
Keyword(s): Birthweight; Ethnic Differences; Gestation/Gestational weight gain; Obesity; Racial Differences

Permission to reprint the abstract has not been received from the publisher.

Objectives: The objectives of the study are to test if weight gain in pregnancy is associated with high birthweight and overweight/obesity in early, middle and late childhood and whether these associations differ by maternal race/ethnicity.

Methods: Mother-child dyads (n = 7539) were included from the National Longitudinal Survey of Youth 1979, a nationally representative cohort study in the USA (1979-2012). Log-binomial regression models were used to analyse associations between weight gain and the outcomes: high birthweight (>4000 g) and overweight/obesity at ages 2-5, 6-11 and 12-19 years.

Results: Excessive weight gain was positively associated, and inadequate weight gain was negatively associated with high birthweight after confounder adjustment (P < 0.05). Only excessive weight gain was associated with overweight in early, middle and late childhood. These associations were not significant in Hispanics or Blacks although racial/ethnic interaction was only significant ages 12-19 years (P = 0.03).

Bibliography Citation
Leonard, Stephanie, Lucia C. Petito, David Rehkopf, Lorrene Ritchie and Barbara Abrams. "Weight Gain in Pregnancy and Child Weight Status from Birth to Adulthood in the United States." Pediatric Obesity 12,S1 (August 2017): 18-25.
4. Leonard, Stephanie
Rasmussen, Kathleen M.
King, Janet C.
Abrams, Barbara
Trajectories of Maternal Weight from Before Pregnancy through Postpartum and Associations with Childhood Obesity
American Journal of Clinical Nutrition 106,5 (November 2017): 1295-1301.
Also: https://doi.org/10.3945/ajcn.117.158683
Cohort(s): Children of the NLSY79, NLSY79, NLSY79 Young Adult
Publisher: American Society for Nutrition (ASN)
Keyword(s): Body Mass Index (BMI); Child Health; Gestation/Gestational weight gain; Modeling, Latent Class Analysis/Latent Transition Analysis; Obesity

Permission to reprint the abstract has not been received from the publisher.

Objective: We described longitudinal trajectories of maternal weight from before pregnancy through the postpartum period and assessed the relations between maternal weight trajectories and offspring obesity in childhood.

Design: We analyzed data from 4436 pairs of mothers and their children in the National Longitudinal Survey of Youth 1979 (1981-2014). We used latent-class growth modeling in addition to national recommendations for prepregnancy BMI, gestational weight gain, and postpartum weight retention to create maternal weight trajectory groups. We used modified Poisson regression models to assess the associations between maternal weight trajectory group and offspring obesity at 3 age periods (2–5, 6–11, and 12–19 y).

Results: Our analysis using maternal weight trajectories based on either latent-class results or recommendations showed that the risk of child obesity was lowest in the lowest maternal weight trajectory group. The differences in obesity risk were largest after 5 y of age and persisted into adolescence. In the latent-class analysis, the highest-order maternal weight trajectory group consisted almost entirely of women who were obese before pregnancy and was associated with a >2-fold increase in the risk of offspring obesity at ages 6-11 y (adjusted RR: 2.39; 95% CI: 1.97, 2.89) and 12-19 y (adjusted RR: 2.74; 95% CI: 2.13, 3.52). In the analysis with maternal weight trajectory groups based on recommendations, the risk of child obesity was consistently highest for women who were overweight or obese at the beginning of pregnancy.

Bibliography Citation
Leonard, Stephanie, Kathleen M. Rasmussen, Janet C. King and Barbara Abrams. "Trajectories of Maternal Weight from Before Pregnancy through Postpartum and Associations with Childhood Obesity." American Journal of Clinical Nutrition 106,5 (November 2017): 1295-1301.
5. Petito, Lucia C.
Leonard, Stephanie
Rehkopf, David
Ritchie, Lorrene
Abrams, Barbara
Maternal Physical Abuse in Childhood is Associated with Offspring Overweight and Obesity in Early Childhood
Presented: Miami FL, Society for Pediatric and Perinatal Epidemiologic Research Annual Meeting, June 2016
Cohort(s): Children of the NLSY79, NLSY79, NLSY79 Young Adult
Publisher: Society for Pediatric and Perinatal Epidemiologic Research
Keyword(s): Body Mass Index (BMI); Child Health; Childhood Adversity/Trauma; Gestation/Gestational weight gain; Intergenerational Patterns/Transmission; Mothers, Health; Obesity; Pregnancy and Pregnancy Outcomes

Permission to reprint the abstract has not been received from the publisher.

Adverse childhood experiences (ACE) have recently been associated with high gestational weight gain (GWG), and high GWG has been associated with child obesity. We hypothesized that maternal ACE exposures are associated with offspring obesity, partially mediated by high GWG. Our study included 4,771 mother-child pairs from the National Longitudinal Survey of Youth (1979-2012). We used log-linear regression models that accounted for the complex survey design to estimate the associations of three maternal ACE measures (physical abuse, mental illness in the household, and alcohol abuse in the household) with the outcomes: ever obese or ever overweight/ obese at ages 2-5 years, 6-11 years, or 12-19 years old. For significant associations, we then estimated the total direct effect by adding GWG (measured with z-scores standardized for gestational duration) to the adjusted regression model. Next, we estimated the natural direct effect by allowing GWG in the model to vary as it would in the absence of the exposure.
Bibliography Citation
Petito, Lucia C., Stephanie Leonard, David Rehkopf, Lorrene Ritchie and Barbara Abrams. "Maternal Physical Abuse in Childhood is Associated with Offspring Overweight and Obesity in Early Childhood." Presented: Miami FL, Society for Pediatric and Perinatal Epidemiologic Research Annual Meeting, June 2016.
6. Vable, Anusha M.
Cohen, Alison K.
Leonard, Stephanie
Glymour, M. Maria
Duarte, Catherine
Yen, Irene H.
Do the Health Benefits of Education Vary by Sociodemographic Subgroup? Differential Returns to Education and Implications for Health Inequities
Annals of Epidemiology 28,11 (November 2018): 759-766.e5.
Also: https://www.sciencedirect.com/science/article/pii/S1047279718305209
Cohort(s): NLSY79
Publisher: Elsevier
Keyword(s): Educational Attainment; Educational Returns; Health, Mental/Psychological; Health/Health Status/SF-12 Scale; Socioeconomic Background

Methods: Using National Longitudinal Survey of Youth 1979 (N=6,158) cohort data, we evaluate education attained by age 25 and mental (MCS) and physical (PCS) health component summary scores at age 50. Race/ethnicity, sex, geography, immigration status, and childhood socioeconomic status (cSES) were evaluated as effect modifiers in birth-year adjusted linear regression models.
Bibliography Citation
Vable, Anusha M., Alison K. Cohen, Stephanie Leonard, M. Maria Glymour, Catherine Duarte and Irene H. Yen. "Do the Health Benefits of Education Vary by Sociodemographic Subgroup? Differential Returns to Education and Implications for Health Inequities." Annals of Epidemiology 28,11 (November 2018): 759-766.e5.