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Author: Mayo, M.S.
Resulting in 1 citation.
1. Li, Chaoyang
Mayo, M.S.
Ahluwalia, Jasjit S.
Maternal Smoking during Pregnancy, Birth Weight, and Childhood Overweight: A Suppression Effect Model
Annals of Epidemiology 13,8 (September 2003): 569.
Also: http://www.sciencedirect.com/science/article/pii/S1047279703001637
Cohort(s): Children of the NLSY79, NLSY79, NLSY79 Young Adult
Publisher: Elsevier
Keyword(s): Birthweight; Body Mass Index (BMI); Breastfeeding; Child Health; Cigarette Use (see Smoking); Hispanics; Intergenerational Patterns/Transmission; Obesity; Pre-natal Care/Exposure; Pre/post Natal Behavior; Pregnancy and Pregnancy Outcomes; Smoking (see Cigarette Use)

METHODS: Children aged 2 to 15 years (mean, 8.6 yrs; SD, 3.5 yrs) in 1996 born to mothers in the National Longitudinal Survey of Youth (NLSY) were studied. The sample (n = 4,850) was 21.4% Hispanic, 29.9% Black, and 48.7% White. Body mass index (BMI) was calculated from measured weight and height, and the BMI-for-age percentile was determined using the revised CDC growth charts. Children with BMI-for-age at or above 85th percentile were defined as overweight. The suppression effects were tested based on the framework proposed by Baron and Kenny (1986) using a series of multiple logistic regression models with SAS-callable SUDAAN program.

RESULTS: After adjusting for sex, ethnicity, gestational age, breastfeeding, mother's age, education, and alcohol use during pregnancy, maternal smoking during pregnancy was significantly associated with childhood overweight without adjusting for birth weight (model 1, total effect tau1 = 0.36, p = 0.006). Maternal smoking during pregnancy was significantly associated with reduced birth weight (model 2, alpha = - 0.21, p<0.0001). The direct effect of maternal smoking on childhood overweight with adjusting for birth weight was increased (model 3, direct effect tau2 = 0.42, p = 0.002). Birth weight was also significantly associated with childhood overweight (model 3, beta = 0.23, p = 0.03). The suppression effect (product of alpha and beta = -0.05, p = 0.04) of birth weight accounted for 14% of the total effects of maternal smoking on childhood overweight.

Bibliography Citation
Li, Chaoyang, M.S. Mayo and Jasjit S. Ahluwalia. "Maternal Smoking during Pregnancy, Birth Weight, and Childhood Overweight: A Suppression Effect Model." Annals of Epidemiology 13,8 (September 2003): 569.